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RESVERATROL
Resveratrol supplementation has been shown to increase lifespan. Resveratrol is a potent Sirtuin activator.
Resveratrol has similar effects on your body as a calorie-restricted diet. Resveratrol reduces your blood pressure, protects your brain, protects your arteries and even has anti-cancer potential.
It would be beneficial to supplement resveratrol alongside NMN and Quercetin. This is because, in order for your sirtuins to perform their beneficial work, we want to activate them with resveratrol and increase their fuel with NMN. Regarding Pure Quercetin, in addition to offering a plethora of health advantages of its own, it also lengthens the half-life of resveratrol and should be taken as part of the same supplement regimen.
Useful links:
- Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
- Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators – PMC
- Resveratrol vs. calorie restriction: data from rodents to humans
- Sirtuin activators mimic caloric restriction and delay ageing in metazoans
- A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
- Resveratrol: A potential challenger against gastric cancer – PMC
- Resveratrol and Cardiovascular Diseases
- Distinct metabolic effects of resveratrol on lipogenesis markers in mice adipose tissue treated with high-polyunsaturated fat and high-protein diets
- Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis
- Resveratrol: A potential challenger against gastric cancer – PMC
- Resveratrol ameliorates atherosclerosis induced by high-fat diet and LPS in ApoE−/− mice and inhibits the activation of CD4+ T cells | Nutrition & Metabolism